The sadly predictable hyping of things nano reached a nadir recently with the promotion of silver nanoparticles (aka “silver bullet”) as a treatment for ebola virus. There has been a great discussion of this and other aspects of silver nanoparticles by Andrew Maynard (here, here for ebola and here for the essential Risk Bites video).
It may surprise some, but until a few weeks ago, there was no simple, direct published method to quantify non-destructively silver nanoparticles. Yet, the non-destructive quantification of silver nanoparticles is essential to any experiment that aims to prepare and use these in a biological context. Without it any experimental work is likely to be qualitative and simple things, such as determining the stoichiometry of functonalisation, become difficult. Indeed, so important is simple quantification of nanoparticles that we validated and published a method for gold nanoparticles in 2007 that has been very well received by the community and which we use daily in the lab. (more…)